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PUBLICATIONS

“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

- Claude Bernard -

Selected Publications

Drivers of heterogeneity in the glioblastoma immune microenvironment (PDF)

Author(s):

Brosque A, Friedmann-Morvinski D.

Source: Curr Opin Cell Biol 2023 Dec.

 

Monocyte-neutrophil entanglement in glioblastoma. (PDF)

Author(s):

Friedmann-Morvinski D, Hambardzumyan D.

Source: J Clin Invest 2023 Jan 3.

 

Cytoskeletal Protein Palladin in Adult Gliomas Predicts Disease Incidence, Progression, and Prognosis (PDF)

Author(s):

Mayer O, Bugis J, Kozlova D, Leemann A, Mansur S, Peerutin I, Mendelovich N, Mazin M, Friedmann-Morvinski D, Shomron N.

Source: Cancers 2022 Oct 19.

 

Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy.(PDF)

Author(s):

Gal O, Betzer O,Rousso-Noori L, Sadan T, Motiei M, Nikitin M, Friedmann-Morvinski D, Popovtzer R, Popovtzer A.

Source: J Nanotheranostics 2022 Sept 30.

 

Differential glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor anngiogenesis and growth  (PDF)

Author(s):

Sengupta S, Mondal M, Prasasvi KR, Mukherjee A, Magod P, Urbach S, Friedmann-Morvinski D, Marin P, Somasundaram K.

Source: Elife 2022 Jun 1.

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Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment  (PDF)

Author(s):

Mastandrea I, Sher D, Magod P, Friedmann-Morvinski D.

Source: STAR Protoc 2022 Jan 20.

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Exploring the longitudinal glioma microenvironment landscape uncovers reprogrammed pro-tumorigenic neutrophils in the bone marrow  (PDF)

Author(s):

Prerna Magod, Ignacio Mastandrea, Liat Rousso-Noori, Lilach Agemy, Guy Shapira, Noam Shomron, and Dinorah Friedmann-Morvinski

Source: Cell Reports 2021 Aug 3.

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P32-specific CAR T cells with dual antitumor and antiangiogenic therapeutic potential in gliomas. (PDF)

Author(s):

Liat Rousso-Noori, Ignacio Mastandrea, Tova Waks, Anat Globerson Levin, Maarja Haugas, Tambet Teesalu, Luis Alvarez-Vallina , Zelig Eshhar, and Dinorah Friedmann-Morvinski

Source: Nat Commun 2021 Jun 14.

 

P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression. (PDF)

Author(s):

Yeini E, Ofek P, Pozzi S, Albeck N, Ben-Shushan D, Tiram G, Golan S, Kleiner R, Sheinin R, Israeli Dangoor S, Reich-Zeliger S, Grossman R, Ram Z, Brem H, Hyde TM, Magod P, Friedmann-Morvinski D, Madi A, Satchi-Fainaro R

Source: Nat Commun 2021 Mar 26.

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CRISPR/Cas9 Genome Editing using Targeted Lipid Nanoparticles for Cancer Therapy. (PDF)

Author(s):

Daniel Rosenblum, Anna Gutkin, Ranit Kedmi, Srinivas Ramishetti, Nuphar  Veiga Ashley M. Jacobi, Mollie S.Schubert, Dinorah Friedmann-Morvinski, Zvi R.Cohen, 3 Mark A. Behlke, Judy Lieberman & Dan Peer.

Source: Science Advances. 2020 Nov 18.

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Tenascin C promotes cancer cell plasticity in mesenchymal glioblastoma. (PDF)

Author(s):

Angel I, Pilo Kerman O, Rousso-Noori L, Friedmann-Morvinski D.

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Source: Oncogene. 2020 Oct 19.

 

5-Hydroxymethylcytosine as a clinical biomarker: Fluorescence-based assay for high-throughput epigenetic quantification in human tissues. (PDF)

Author(s):

Margalit S, Avraham S, Shahal T, Michaeli Y, Gilat N, Magod P, Caspi M, Loewenstein S, Lahat G, Friedmann-Morvinski D, Kariv R, Rosin-Arbesfeld R, Zirkin S, Ebenstein Y.

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Source: Int J Cancer. 2020 January 1​

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Peptide-guided nanoparticles for glioblastoma targeting. (PDF)

Author(s):

Säälik P, Lingasamy P, Toome K, Mastandrea I, Rousso-Noori L, Tobi A, Simón-Gracia L, Hunt H, Paiste P, Kotamraju VR, Bergers G, Asser T, Rätsep T, Ruoslahti E, Bjerkvig R, Friedmann-Morvinski D*, Teesalu T*.

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Source: IJ Control Release. 2019 August 28

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Organelle-Targeted BODIPY Photocages: Visible-Light-Mediated Subcellular Photorelease. (PDF)

Author(s):

Kand D, Pizarro L, Angel I, Avni A, Friedmann-Morvinski D, Weinstain R.

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Source: Angew Chem Int Ed Engl. 2019 March 26

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Cleavage of the leptin receptor by matrix metalloproteinase-2 promotes leptin resistance and obesity in mice. (PDF)

Author(s):

Rafi Mazor*, Friedmann-Morvinski Dinorah*, Tom Alsaig, Oded Kleifeld, Erik B Kistler, Liat Rousso-Noori, Cheng Huang, Joyce B Li, Verma M. Inder Geert W Schmid-Schonbein.

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Source: Sci Transl Med 2018 August 22

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Targeting NF-kB in glioblastoma: A therapeutic approach. (PDF)

Author(s):

Friedmann-Morvinski Dinorah, Narasimamurthy Rajesh, Xia Yifeng, Myskiw Chad, Soda Yasushi, Verma M. Inder.

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Source: Science Advances 2016 January 8

 

Identification of therapeutic targets for glioblastoma by network analysis. (PDF)

Author(s):

Friedmann-Morvinski Dinorah, Bhargava Vipul, Gupta Shakti, Verma M. Inder, Subramaniam Shankar.

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Source: Oncogene. 2016 Feb 4

 

Glioblastoma heterogeneity and cancer cell plasticity.

Author(s):

Friedmann-Morvinski Dinorah

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Source: Crit Rev Oncog. 2014

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Dedifferentiation and reprogramming: origins of cancer stem cells. (PDF)

Author(s):

Friedmann-Morvinski Dinorah and Verma M. Inder.

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Source: EMBO Rep. 2014 Mar

 

Proapoptotic peptide-mediated cancer therapy targeted to cell surface p32. (PDF)

Author(s):

Agemy Lilach, Kotamraju V Ramana, Friedmann-Morvinski Dinorah, Sharma S, Sugahara KN, Ruoslahti Erkki.

 

Source: Mol Ther. 2013 Dec

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Overexpression Models: Lentiviral Modeling of Brain Cancer. (PDF)

Author(s):

Friedmann-Morvinski Dinorah, and Singer Oded.

 

Source: Curr Protoc Mouse Biol. 2013 Jun

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Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. (PDF)

Author(s):

Niola F, Zhao X, Singh D, Sullivan R, Castano A, Verrico A, Zoppoli P, Friedmann-Morvinski D, Sulman E, Barrett L, Zhuang Y, Verma I, Benezra R, Aldape K, Iavarone A, Lasorella A.

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Source: J Clin Invest. 2013 Jan

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Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. (PDF)

Author(s):

Friedmann-Morvinski Dinorah, Bushong Eric A, Ke Eugene, Soda Yasushi, Marumoto Tomotoshi, Singer Oded, Ellisman Mark H, Verma Inder M.

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Source: Science. 2012 Nov 23

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Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. (PDF)

Author(s):

Agemy L, Friedmann-Morvinski D, Kotamraju VR, Roth L, Sugahara KN, Girard OM, Mattrey RF, Verma IM, Ruoslahti E.

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Source: PNAS. 2011 Oct 18

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Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. (PDF)

Author(s):

Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas JC, Gill RM, Huillard E, Liu C, Zong H, Rowitch DH, Barres BA, Verma IM, Kosik KS.

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Source: Oncogene. 2012 Apr 12

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Transdifferentiation of glioblastoma cells into vascular endothelial cells. (PDF)

Author(s):

Soda Y, Marumoto T, Friedmann-Morvinski D, Soda M, Liu F, Michiue H, Pastorino S, Yang M, Hoffman RM, Kesari S, Verma IM.

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Source: PNAS 2011 Mar 15

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Development of a novel mouse glioma model using lentiviral vectors. (PDF)

Author(s):

Marumoto T, Tashiro A, Friedmann-Morvinski D, Scadeng M, Soda Y, Gage FH, Verma IM.

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Source: Nat Med. 2009 Jan

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